Prevalence of Rotavirus, Adenovirus, and Rotavirus denovirus Coinfection among children less than 5 years in Kirkuk city

Abstract

Infectious gastroenteritis is one of most important causes of morbidity and mortality in children < 5 years age. Rotavirus and enteric adenoviruses are the most important agents of infectious gastroenteritis. Little is known about the epidemiology of rotavirus and adenovirus gastroenteritis in our region. This study was aimed to determine the frequency of rotavirus and enteric adenovirus gastroenteritis in pediatric patients admitted to Kirkuk pediatric hospital. Fresh stool specimens of 177 children < 5 years age patients admitted to Kirkuk pediatric hospital during Jan-May 2012 due to acute gastroenteritis were studied. Rotavirus and enteric adenovirus antigens were investigated in the fresh stool specimens with the qualitative Latex for Rotavirus and Rota-Adeno immunochromatographic test for both Rotavirus and Adenovirus. Using latex agglutination viral antigens were determined In 30 (16.9%) of the fresh stool specimens. Of these 30 specimens, rotavirus was established in 10 (33.3%), enteric adenovirus in 2 (6.6%), both rotavirus and enteric adenovirus in 10 (33.3%) and 8 (26.6%) were negative for both Rota-Adenovirus using immunochromatographic test.. Rotavirus antigen was detected in 36.6 % of patients infants between 7 and 12 months of age were most frequently infected