Effect of Iron Overdose on Histological Pictures of Liver and Kidneys of Neonate Rabbits

Abstract

Twenty neonate Rabbits were used, and divided into two groups. The first group (control) includes 10 neonate Rabbits, while the second 10 neonate Rabbits were the experimental and received 25mg\kg iron sulphat dissolved in D.W. (suspension)\day for one month duration. The toxic effects of iron were clear in the different tissue. The histological change were clear in the hepatic cell atrophy, irregular hepatic cells, RBC cells in the blood sinusoid. However, the kidney tissue showed rupture or absence of Bowman's capsule, atrophy of glomeruli, and lymphatic cells infiltration. the distal convoluted tubules were lined with low cuboidal cells.